Preheat oven to 425°F, cut broccoli into florets, mince garlic, and toss broccoli with 2 tablespoons olive oil, garlic, salt, and pepper on a sheet pan.
Roast broccoli for 10 minutes, then push to the sides and place salmon fillets skin-side down in the center.
Drizzle salmon with remaining 2 tablespoons oil, squeeze lemon juice over top, season with salt and pepper, and roast for 8 minutes until salmon flakes easily.
Divide salmon and broccoli among plates and serve with lemon wedges.